Discover how elevated Letm1 protein drives mitochondrial dysfunction and triggers heart cell apoptosis in this engaging scientific exploration.
Discover how bacterial LPS triggers neuron apoptosis in dental pulp through TNF-α and cytochrome c pathways, leading to tooth nerve death.
Discover how MLN4924 and TRAIL combine to overcome cancer resistance through JNK-dependent c-FLIP downregulation in head and neck cancer cells.
Exploring the Fc receptor off-signal mechanism that triggers apoptosis in B cells and maintains immune system balance
Discover how Gentamicin, a life-saving antibiotic, causes permanent hearing loss through ROS and JNK signaling pathways, and the research that could lead to protective treatments.
Discover how Gentian Violet, a century-old antiseptic, shows remarkable potential in fighting Cutaneous T-Cell Lymphoma by triggering cancer cell apoptosis and inhibiting proliferation.
Discover how sodium butyrate, a gut-produced molecule, triggers apoptosis in breast cancer cells through ROS formation and mitochondrial impairment.
Explore how researchers are enhancing cancer therapy by targeting the c-FLIPL protein to make cancer cells more susceptible to programmed cell death.
Discover how Pleurotus highking mushroom induces apoptosis in breast cancer cells by altering gene balance and inhibits tumor sphere formation.
Discover how high-dose aspirin initiates cellular suicide in spiral ganglion neurons, leading to hearing loss and tinnitus through caspase-3 activation.